At least 25 Palestinians were killed in Israeli strikes across the Gaza Strip on Wednesday, according to the Hamas-run health ministry, marking one of the deadliest days since a ceasefire came into effect five weeks ago.

Ten casualties were reported from a strike on a religious endowments ministry building in the eastern Zeitoun neighborhood of Gaza City. The Israeli military stated that the strikes were in response to gunfire directed at their soldiers in Khan Younis, which they claim violated the ceasefire agreement.

Hamas responded by denouncing the Israeli actions as a dangerous escalation that threatens the tenuous ceasefire.

This uptick in violence comes on the heels of a UN Security Council resolution supporting U.S. President Trump's Gaza peace plan following years of conflict.

Mahmoud Bassal, a spokesman for Gaza's Civil Defence, noted that multiple locations, including Gaza City and Khan Younis, were struck shortly after sunset on Wednesday, leading to significant destruction and civilian casualties.

The strikes have drawn international condemnation, with calls for the U.S. to pressure Israel to maintain the ceasefire. In contrast, U.S. officials claim that Hamas had intended to disrupt the ceasefire.

The situation in Gaza remains dire, with humanitarian crises persisting as violence escalates. The residents continue to face challenges amid ongoing military operations that threaten their safety and well-being.