Jenks, a two-time All-Star, made history by throwing the final pitch in Game 4 of the 2005 World Series, marking the franchise's first championship in 88 years. White Sox chairman Jerry Reinsdorf expressed deep sorrow at the loss, honoring Jenks' significant contributions to the team and his place in White Sox history. After a successful six-season career in Chicago, he briefly played for the Boston Red Sox in 2011, but injuries limited his performance. Having relocated to Portugal last year, Jenks was undergoing treatment for his illness before his untimely passing.

The outpouring of grief from fans and teammates underscores Jenks' impact on not just the Chicago White Sox, but on the sport of baseball.