In a press briefing on February 21, 2025, at the Policlinico Agostino Gemelli in Rome, Dr. Sergio Alfieri, the pope's surgeon, and Dr. Luigi Carbone, his primary medical doctor, provided updates on the pontiff's health. They confirmed that the 88-year-old pope has been battling a bronchial infection leading to double pneumonia but remains off a respirator. Dr. Carbone noted that although the infection is not immediately life-threatening, the pope is "not out of danger."

Despite his critical condition, the pope's spirits appear buoyed, as he reportedly maintained a sense of humor during the briefing, even joking with his doctors. However, he expressed awareness of the gravity of his situation, acknowledging his chronic health issues. "The situation at my age is grave," he reportedly told Dr. Alfieri, who conveyed these sentiments in his report to the media. The doctors acknowledged the fragility of the situation, underscoring that one misstep could shift the balance of his health.

Given the pontiff’s previous lung surgery and the current nature of his illness, there are rising concerns about what his continued health challenges may mean for the Catholic Church, which hosts nearly 1.4 billion believers globally. The potential for Francis to resign has been a topic of discussion, following historical precedents set by Pope Benedict XVI.

As the Vatican navigates this uncertain period, Dr. Alfieri described Francis as "fragile but tough," while Dr. Carbone highlighted his refusal to give up. In a positive sign during the ongoing treatment, the pope managed to take time to pray in a hospital chapel, showcasing his resilience amidst adversity.

With speculative questions lingering about the future leadership of the Catholic Church, the medical teams continue to monitor the pope's condition closely, ensuring that any decisions regarding his care account for both his health status and his enduring dedication to his role.